Table 6.
Characteristics of the cohort of uveal melanoma (UM) patients enucleated in the LUMC between 1999 and 2008 (n = 64).
| Characteristics | Number of Cases or Mean | % of Cases or SD | |
|---|---|---|---|
| Gender | Male | 33 | 51% |
| Female | 31 | 49% | |
| Age at enucleation (in years) | 61 | ±15.7 | |
| Cell type | Spindle | 22 | 33% |
| Mixed/epithelioid | 41 | 62% | |
| Ciliary body involvement | No | 40 | 61% |
| Yes | 24 | 36% | |
| Chromosome 3 status | Disomy | 24 | 46% |
| Monosomy | 40 | 61% | |
| BAP1 Staining | Positive | 25 | 46% |
| Negative | 30 | 55% | |
| Unknown | 9 | 16% | |
| GNA11 mutation | No | 31 | 48% |
| Yes | 33 | 52% | |
| GNAQ mutation | No | 36 | 56% |
| Yes | 28 | 44% | |
| Chromosome 6p gain | No | 43 | 65% |
| Yes | 21 | 32% | |
| Chromosome 8q gain | No | 19 | 29% |
| Yes | 45 | 68% | |
| Metastasis | No | 27 | 42% |
| Yes | 37 | 58% | |
| Follow-up time (in months) | 77 | ±55 | |
| Vital status | Dead due to UM metastasis | 37 | 58% |
| Dead due to other causes | 6 | 10% | |
| Cause of death unknown | 3 | 5% | |
| Alive at last follow-up date | 18 | 28 |