Table 3.

Mean expression of mRNA expression of HLA Class I antigens and infiltrating immune cells in relation to the GNA11 or GNAQ mutation. p-values were calculated using the Wilcoxon-Rank sum test. STD = standard deviation.

mRNA Probe	Illumina	D3 GNA11 n = 9 Mean ± STD	D3 GNAQ n = 12 Mean ± STD	M3 GNA11 n = 23 Mean ± STD	M3 GNAQ n = 15 Mean ± STD	M3 GNA11 versus M3 GNAQ p-Value	D3 GNA11 versus D3 GNAQ p-Value	All M3 versus All D3 p-Value
HLA_A	ILMN 1671054	10.69 ±0.74	10.89 ±0.73	11.85 ±0.84	11.67 ±0.68	0.30	0.34	<0.001
HLA_A	ILMN 2203950	13.16 ±0.96	13.38 ±0.64	14.26 ±0.53	14.13 ±0.49	0.42	0.13	<0.001
HLA_A	ILMN 2186806	9.87 ±2.08	9.89 ±0.89	11.31 ±1.07	11.13 ±1.22	0.79	0.27	<0.001
HLA_B	ILMN 1778401	10.25 ±2.24	10.18 ±1.09	11.98 ±1.40	12.05 ±1.10	0.95	0.21	<0.001
HLA_C	ILMN 2150787	6.57 ±0.74	6.22 ±0.41	6.52 ±0.64	6.53 ±0.75	0.46	0.21	0.38
HLA_C	ILMN 1721113	7.63 ±1.18	7.46 ±0.53	8.20 ±1.21	8.35 ±1.13	0.70	0.80	0.013
HLA_E	ILMN 1765258	11.10 ±1.52	10.84 ±0.59	11.83 ±1.11	11.73 ±0.85	0.74	0.75	<0.001
HLA_F	ILMN 1762861	7.65 ±1.18	7.65 ±0.70	8.64 ±1.17	8.46 ±0.97	0.68	0.59	<0.001
HLA_G	ILMN 1656670	8.25 ±1.48	8.08 ±0.64	9.05 ±0.76	8.88 ±0.70	0.39	0.70	<0.001
CD68	ILMN 1714861	10.36 ±1.30	10.37 ±0.86	11.07 ±0.75	11.01 ±0.82	0.95	0.70	0.008
CD3D	ILMN 2261416	7.07 ±1.70	6.66 ±0.40	7.28 ±1.12	7.28 ±1.16	0.95	0.92	0.03
CD3D	ILMN 2325837	7.14 ±1.71	6.57 ±0.43	7.37 ±1.23	7.31 ±1.16	0.98	0.46	0.022
CD3E	ILMN 1739794	6.56 ±0.50	6.38 ±0.07	6.51 ±0.28	6.57 ±0.31	0.55	0.50	0.19
CD3G	ILMN 1717197	6.68 ±0.45	6.53 ±0.11	6.63 ±0.28	6.57 ±0.29	0.39	0.64	0.77
CD8A	ILMN 1768482	7.30 ±2.06	6.78 ±0.45	7.45 ±1.23	7.54 ±1.29	0.86	0.86	0.06
CD8A	ILMN 1760374	6.58 ±0.58	6.36 ±0.10	6.47 ±0.29	6.54 ±0.45	0.63	0.27	0.25
CD8A	ILMN 2353732	7.22 ±2.11	6.65 ±0.43	7.42 ±1.25	7.46 ±1.31	0.98	0.80	0.022
CD4	ILMN 1727284	6.65 ±0.49	6.54 ±0.29	6.69 ±0.24	6.73 ±0.36	0.98	0.86	0.044