Table 1.
Factors influencing IBD quality of life.
| Univariate analysis | Multivariate model: backward elimination | |||
|---|---|---|---|---|
| Variables |
N
435 |
Unadjusted OR Risk of having pathological IBDQ (≤170) |
Adjusted OR Risk of having pathological IBDQ (≤170) |
Adjusted OR Risk of having pathological IBDQ (≤170) |
| Disease | ||||
| CD | 203 | 1 | 1 | 1 |
| UC | 232 | 0.59 (0.40-0.88) | 0.44 (0.28-0.71) | 0.44 (0.28-0.70) |
| Age group | ||||
| <45 | 189 | 1 | ||
| ≥45 | 246 | 1.19 (0.80-1.76) | ||
| Sex | ||||
| Men | 231 | 1 | ||
| Women | 204 | 1.20 (0.81-1.76) | ||
| Disease latency | ||||
| ≤1 year | 335 | 1 | ||
| >1 year | 100 | 1.03 (0.96-1.11) | ||
| Disease duration | ||||
| ≤5 years | 80 | 1 | ||
| >5 years | 355 | 0.99 (0.97-1.01) | ||
| Current smoking status | ||||
| Nonsmoker | 371 | 1 | ||
| Smoker | 64 | 0.17 (0.68-2.01) | ||
| Current alcohol intake | ||||
| No | 189 | 1 | 1 | |
| Yes | 246 | 0.63 (0.42-0.92) | 0.69 (0.44-1.07) | |
| Disease active (pMayo > 1 or HBI > 4) | ||||
| Inactive | 332 | 1 | 1 | 1 |
| Active | 103 | 5.62 (3.47-9.12) | 5.47 (3.11-9.61) | 5.67 (3.30-9.76) |
| High faecal calprotectin (>250) | ||||
| No | 248 | 1 | 1 | |
| Yes | 187 | 1.90 (1.28-2.82) | 1.18 (0.74-1.87) | |
| Anaemia (Hb < 12 females, <13 males) | ||||
| No | 373 | 1 | 1 | 1 |
| Yes | 62 | 2.69 (1.68-5.80) | 2.05 (1.09-3.86) | 2.15 (1.15-4.03) |
| UC localization | ||||
| E1/E2 | 123 | 1 | ||
| E3 | 109 | 1.34 (0.77-2.33) | ||
| CD behavior | ||||
| Nonstricturing, nonpenetrating | 104 | 1 | ||
| Stricturing | 65 | 1.01 (0.54-1.89) | ||
| Penetrating | 34 | 1.26 (0.58-2.73) | ||
| Localization | ||||
| L1 terminal ileum | 48 | 1 | ||
| L2 colon or L3 ileocolon | 148 | 1.19 (0.61-2/29) | ||
| L4 upper or upper+other | 7 | 1.86 (0.37-9.27) | ||
| Extraintestinal manifestations | ||||
| No | 326 | 1 | 1 | 1 |
| Yes | 109 | 3.89 (2.47-6.14) | 3.08 (1.87-5.08) | 3.15 (1.92-5.18) |
| Immunosuppressant | ||||
| No | 381 | 1 | ||
| Yes | 54 | 1.19 (0.67-2.12) | ||
| Biologics | ||||
| No | 262 | 1 | ||
| Yes | 173 | 1.42 (0.96-2.10) | ||
| Surgery | ||||
| No | 320 | 1 | ||
| Yes | 115 | 1.36 (0.88-2.10) | ||