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. 2019 Jul 25;8(8):774. doi: 10.3390/cells8080774

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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TBMS1 blocks glioblastoma cells migration and invasion. (a) The migration ability of glioblastoma cells treated with different concentrations of TBMS1 was measured by wound-healing assay. DMSO was added as a control. (b) According to (a) plot, the percentage of cell healing was counted under different TBMS1 concentrations. (c) The invasion ability of glioblastoma cells treated with different concentrations of TBMS1 was measured by Transwell assay. DMSO was added as a control. (d) The expression levels of MMP7, MMP2, Snail, Slug, and Tubulin proteins in LN229 and U87 cells were measured by western blot treated with different concentrations of TBMS1. DMSO was added as a control. ** p < 0.01, *** p < 0.001, p-values < 0.05 were considered as statistically significant.