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. 2019 Aug 12;11(8):1155. doi: 10.3390/cancers11081155

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Example of zonal analysis on histopathology. (A) Method that was developed for calculation of microsphere deposition density. 1 and 2 = non-neoplastic tissue (NNT), 3 = Tumour centre, 4 = 1–2 mm zone within tumour border, 5 = 0–1 mm zone within tumour border, 6 = 0–1 mm zone away from tumour border, 7 = 1–2 mm zone away from tumour border. Slide magnification = 0.3×. (B) Illustration of the 1 mm and 2 mm zones from the tumour margin that microsphere densities were measured within. The highest density was found within 1 mm from the tumour periphery.