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Changes in serum levels of C3M and C4M between baseline and surgery according to treatment arm.
| Changes in Serum Levels | C3M n (%) | C4M n (%) | ||||
|---|---|---|---|---|---|---|
| Total | Trastuzumab | Lapatinib | Total | Trastuzumab | Lapatinib | |
| Increase ≥20% | 24 (22.6%) | 12 (23.1%) | 12 (22.2%) | 25 (23.6%) | 12 (22.6%) | 13 (24.5%) |
| No change 1 | 43 (40.6%) | 20 (38.5%) | 23 (42.6%) | 58 (54.7%) | 29 (54.7%) | 29 (54.7%) |
| Decrease ≥20% | 39 (36.8%) | 20 (38.5%) | 19 (35.2%) | 23 (21.7%) | 12 (22.6%) | 11 (20.8%) |
1 defined as an increase <20% or decrease <20%.
