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Inhibition of miR-497, miR-1268a, or miR-665 prevents the hypoxia-induced proliferation of VSMCs. (Left panel) Representative images of Ki-67 immunostaining of control, anti-miR-497, anti-miR-1268a, or anti-miR-665-transfected PASMCs after exposure to normoxia or hypoxia for 24 h. Scale bar represents 20 μm. (Right panel) Calculation of Ki-67 index. * p < 0.001; ** p < 0.0001.
