Skip to main content
. 2019 Jul 24;8(8):768. doi: 10.3390/cells8080768

Figure 5.

Figure 5

Syx18 may function together with Sec20 in autophagy regulation. (A–E) Use1 (A), Sec22 (B), Zw10 (C), or Syx18 (D) was silenced in the GFP+ cells, and autophagy was assessed by 3xmCherry-Atg8a expressed ubiquitously. Solely the knockdown of Syx18 altered the distribution of the reporter, raising the possibility that it is the only one of the previously known partners of Sec20 that also regulates autophagy. (E) Quantification of the area of 3xmCherry-Atg8a dots. Medians are shown as horizontal black lines within the boxes. Bars show the upper and lower quartiles, and the whiskers plot the smallest and largest observations. NS: non-significant (p ≥ 0.05), *** p < 0.001, scale bars: 10 μm.