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. 2019 Jul 24;8(8):768. doi: 10.3390/cells8080768

Figure 6.

Figure 6

Syx18 regulates endocytic trafficking and degradation. (A–E) Control (A), Use1- (B), Sec22- (C), Zw10- (D) and Syx18-depleted (E) garland nephrocytes were immunostained against early endosomal Rbsn-5 and late endosomal Rab7. Only Syx18 depletion caused enlargement of late endosomes similar to Sec20 RNAi nephrocytes (see Figure 1A,B). (F) Quantification of the areas of Rab7-positive vesicles. Medians are shown as horizontal black lines within the boxes. Bars show the upper and lower quartiles, and the whiskers plot the smallest and largest observations. NS: non-significant (p ≥ 0.05), *** p < 0.001, scale bars: 20 μm.