Table 3.
Comparison of patients clinically diagnosed with FNMTC and screened FNTMC to patients from the SEER database
| Groups (number) | Clinically diagnosed FNMTC (58) | Screened FNMTC (20) | SEER (53571) | P value* | P value† |
|---|---|---|---|---|---|
| Age | .038 | .310 | |||
| <45 y | 62.1 | 57.9 | 49.5 | ||
| ≥45 y | 37.9 | 42.1 | 50.5 | ||
| Female:male | 2.8 | 2.1 | 3.6 | .268 | .217 |
| Surgery (%) | |||||
| Less than lobectomy | 0 | 0 | 0.9 | .019 | .905 |
| HT | 1.8 | 15.8 | 14.5 | ||
| TT | 98.2 | 84.2 | 84.6 | ||
| Histopathology (%) | |||||
| Classic | 80.7 | 94.7 | 63.2 | .02 | .017 |
| PTCFV | 14 | 5.3 | 30.2 | ||
| PTCTCV/FTC | 5.3 | 0 | 6.6 | ||
| ETE (%) | 12.5 | 0 | 15.4 | .355 | .05 |
| TNM stage (%) | |||||
| T | .112 | .05 | |||
| T0 | 0 | 0 | 0.1 | ||
| T1 | 68.5 | 94.7 | 57.8 | ||
| T2 | 9.3 | 5.3 | 19.1 | ||
| T3 | 14.8 | 0 | 18.6 | ||
| T4a | 7.4 | 0 | 2.9 | ||
| T4b | 0 | 0 | 1.4 | ||
| N | .003 | .575 | |||
| N0 | 56.4 | 78.9 | 78.6 | ||
| N1NOS | 9.1 | 5.3 | 4.2 | ||
| N1a | 23.6 | 15.8 | 10.1 | ||
| N1b | 10.9 | 0 | 7.1 | ||
| M | .521 | .808 | |||
| M0 | 100 | 100 | 98.9 | ||
| M1 | 0 | 0 | 1.1 |
*
comparison of clinically diagnosed FNMTC to SEER
†
comparison of FNMTC diagnosed by screening to SEERPTC, papillary thyroid cancer; PTCFV, follicular variant of PTC; PTCTCV, tall-cell variant of PTC; FTC, follicular thyroid cancer; HT, hemithyroidectomy; TT, total thyroidectomy; ETE, extrathyroidal extension;