Skip to main content
. 2019 Jul 30;8(8):794. doi: 10.3390/cells8080794

Figure 9.

Figure 9

LA potentiates cell death induction in CRC upon treatment with the anticancer drugs Doxo and 5-FU. (A) Cells were pre-treated with LA for 48 h (250 µM for HCT116 and HCT116-p53−/−; 100 µM for RKO), then supplemented with either Doxo (1 µM for HCT116 and RKO; 5 µM for HCT116-p53−/−) or 5-FU (5 µM for HCT116; 20 µM for HCT116-p53−/−; 10 µM for RKO) and treated for another 72 h. After 120 h, cells were collected for cell death measurements and subjected to AnnexinV /PI staining followed by flow cytometry. Data is presented as mean + SEM (n≥3). Ns: p > 0.05; * p < 0.05; *** p < 0.001; **** p < 0.0001. (B) Representative dot plots for experiments shown in (A).