Table 8.
Genotype distribution of allele frequencies of HLA-E polymorphism in living-donor kidney transplant recipients (A) and corresponding donors (B) with respect to BK polyomavirus nephropathy (PyVAN) or cytomegalovirus (CMV) infection.
| (A) Recipient HLA-E genotype |
PyVAN or CMV Infection
N = 46 |
No PyVAN and no CMV Infection N = 267 | p-Value | OR | 95% CI |
| 01:03/01:03 | 12 (26.1%) | 52 (22.4%) | 0.57 | 1.22 | 0.59–2.53 |
| 01:01/01:03 | 28 (60.9%) | 106 (45.7%) | 0.07 | 1.85 | 0.96–3.53 |
| 01:01/01:01 | 6 (13.0%) | 74 (31.9%) | 0.012 * | 0.32 | 0.13–0.79 |
| Allele Frequencies | |||||
| 01:03 | 52 | 210 | 0.052 | 1.57 | 1.00–2.47 |
| 01:01 | 40 | 254 | |||
| (B) Donor HLA-E genotype |
PyVAN or CMV Infection
N = 46 |
No PyVAN and no CMV Infection
N = 267 |
p-Value | OR | CI (95%) |
| 01:03/01:03 | 12 (9.1%) | 51 (22.0%) | 0.44 | 1.33 | 0.64–2.79 |
| 01:01/01:03 | 26 (81.8%) | 122 (52.6%) | 0.75 | 1.17 | 0.62–2.22 |
| 01:01/01:01 | 8 (9.1%) | 59 (25.4%) | 0.34 | 0.62 | 0.27–1.39 |
| Allele Frequencies | |||||
| 01:03 | 50 | 224 | 0.31 | 1.3 | 0.81–1.99 |
| 01:01 | 42 | 240 | |||
* p < 0.05.