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. 2019 Aug 11;8(8):873. doi: 10.3390/cells8080873

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Top diseases and biological functions related to the hNgb protein interactors in a non-stress condition. (a) Network analysis by Ingenuity Pathway Analysis reveals the 24 specific hNgb interactors to be specifically linked to neurological diseases and organismal injury and abnormalities. The proteins involved are: 78 kDa glucose-regulated protein (HSPA5), L-lactate dehydrogenase B chain (LDHB), phosphoglycerate kinase 1 (PGK1), 60S ribosomal protein L15 (RPL15), 40S ribosomal protein S4 X isoform (RPS4X), ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCHL1), and vimentin (VIM). (b) Function annotations of the neurological diseases network show a clear link to motor neuropathies.