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. 2019 Aug 5;8(8):839. doi: 10.3390/cells8080839

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Comparison of FW imaging (MD_T, AD_T, and FW) indices between the healthy controls and the patients with PD. GBSS analyses showed that the patients with PD had significantly higher MD_T, AD_T, and FW (red-yellow voxels) compared with the healthy controls (p < 0.05, FWE-corrected). The skeleton is presented in green. To aid visualization, the results are thickened using the fill script implemented in the FMRIB Software Library. AD, axial diffusivity; AD_T, FW-corrected axial diffusivity; FW, free water; GBSS, gray matter-based spatial statistics; MD, mean diffusivity; MD_T, FW-corrected mean diffusivity; PD, Parkinson’s disease.