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. 2019 Aug 7;8(8):845. doi: 10.3390/cells8080845

Figure 4.

Figure 4

Gene alterations in NASH. Gene alterations/modifications associated with the pathogenesis of NASH affect the GCKR, TM6SF2, PNPLA3, and MBOAT7 genes. The chromosomal location of respective genes is depicted in the ideogram. Gene annotations were done with the Genome Decoration Page (https://www.ncbi.nlm.nih.gov/genome/tools/gdp) and genomic coordinates deposited in the Online Mendelian Inheritance in Man (OMIM) database under accession no. 609567 (PNPLA3, 22q13.31), 606563 (TM6SF2, 19p13.11), 606048 (MBOAT7, 19q13.42), and 600842 (GCKR, 2p23.3).