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. 2019 Aug 6;8(8):842. doi: 10.3390/cells8080842

Figure 4.

Figure 4

Box and whisker plots of the expression of 12 differentially expressed DNA repair genes associated with post-chronic Cd exposure. Two datasets, (A) lung adenocarcinoma samples and (B) lung squamous cell carcinoma samples with different smoking history, were analyzed. Data were derived from The Cancer Genome Atlas (TCGA, provisional) and sorted using cBioPortal database. The box and whiskers plots are plotted in the style of 10–95 percentile. Smoking status: A = lifelong non-smoker (76 samples for lung adenocarcinoma; 18 samples for lung squamous cell carcinoma samples); B = current smoker (119 samples; 133 samples); C = current reformed smoker for ≤15 years (135 samples; 250 samples); D = current reformed smoker for >15 years (169 samples; 83 samples). Two-tailed Student’s t-test was used to determine significant differences between the means of the groups. p ≤ 0.05 was considered statistically significant. * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001; **** p ≤ 0.0001.