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. 2019 Aug 9;8(8):864. doi: 10.3390/cells8080864

Figure 1.

Figure 1

PRCAT38 is an androgen-regulated, prostate cancer-specific lncRNA that modulates cell growth and cell migration. (a) PRCAT38 is highly induced by DHT in LNCaP and VCaP cells, but not DU145 cells. (b) Androgen induction of PRCAT38 is inhibited by the androgen receptor antagonist bicalutamide in LNCaP and VCaP cells. (c) Nuclear-cytoplasmic fractionation showing the subcellular location of PRCAT38, GAPDH and U1 in LNCaP and VCaP cells. (d) growth of LNCaP cells before and after PRCAT38 knockdown. (e) Migration of LNCaP cells before and after PRCAT38 knockdown. Data are shown as the mean ± SD (n = 3). *: P < 0.05, **: P < 0.01, ***: P < 0.001, ns: not significant.