Prof. David Finlay |
Trinity College, Dublin, Ireland |
Fuelling robust anti-tumour natural killer (NK) cell responses |
Metabolic drugs might synergistically enhance immunotherapy via metabolic reprogramming of the tumour microenvironment (TME). |
Prof. Peter Jones |
Van Andel Institute, Grand Rapids, Michigan, U.S. |
Epigenetic therapies |
Epigenetic treatments are already incorporated into clinical practice for blood-related malignancies and are actively investigated in combination with conventional therapies in solid tumours. Further understanding of their mechanisms also reveals a possible link with enhancing patients’ immune response. |
Dr. Noel McCaffrey |
Dublin City University, Ireland |
Community-based exercise in cancer survivorship |
While physical exercise is not currently being used in specific combination therapies, it is emerging as a very promising intervention for cancer management and will undoubtedly gain centre stage in the future as a novel approach to target cancer cells. |
Dr. Gillian Prue |
Queen’s University, Belfast, Northern Ireland |
When exercise is the drug: can activity levels really be used to treat prostate cancer? |
Dr. Sara Charmsaz |
Royal College of Surgeons in Ireland, Ireland |
RNA-methylation in Estrogen Receptor (ER)-positive breast cancer |
The development of ‘omics’ technologies will allow us to better predict the response to combination therapies, thus improving our ability to use them in the clinic. |