Table E1.
Subject III.1's routine clinical laboratory investigations
| Laboratory investigations | Subject III.1 (reference range) |
|---|---|
| Autoantibodies persistent >3 mo | Absent∗ |
| Hemoglobin | 10 g/L (120-160 g/L) |
| Platelet count | 182 × 109/L (150-450 × 109/L) |
| WBC count | 6.25 × 109/L (4.0-11 × 109/L) |
| Lymphocyte subsets | Normal |
| IgG | 19.9 g/L (3.1-13.8 g/L) |
| IgA | 1.94 g/L (0.4-0.7 g/L) |
| IgM | 2.29 g/L (0.5-2.2 g/L) |
| IgD | 7 kU/L (2-100 kU/L) |
| Adenovirus, CMV, EBV, HSV, VZV, parechovirus PCR | Negative |
| Toxoplasma species PCR | Negative |
| Mycoplasma species antibodies | Negative |
| QuantiFERON | Negative |
| Nitroblue tetrazolium test | Normal |
| Brucella species serology | Negative |
| Toxocara species serology | Normal |
| 16s PCR and 18s PCR CSF | Negative |
| JC and BK virus | Negative |
| Complement C3 | 1.77 g/L (0.75-1.65 g/L) |
| Complement C4 | 0.24 g/L (0.14-0.54 g/L) |
| Liver enzymes | ALT: 15 U/L (10-25 U/L) ALP: 96 U/L (150-380 U/L) |
| CSF white cell count | <1 × 106 |
| CSF cytospin | Negative |
| CSF oligoclonal bands | Negative |
CSF, Cerebrospinal fluid.
∗
Autoantibodies tested were as follows: antinuclear antibodies, anti-neutrophil cytoplasm antibodies, rheumatoid factor, anti-tissue transglutaminase antibodies, anti-thyroid peroxidase antibodies, anti-myelin oligodendrocyte antibodies, anti-yo, anti-hu, anti-ri antibodies, N-methyl-D-aspartate receptor antibodies, rheumatoid factor antibodies, celiac screen antibodies, β2-glycoprotein, and anti-cardiolipin antibodies.