Table 1.

Final patent rats included in all data analyses. Catheter patency checks were routinely conducted throughout the experiments to ensure rats were properly receiving i.v. TsA or vehicle pretreatment, and to ensure adequate i.v. amphetamine self-administration. Non-patent rats were excluded from behavioral procedures and all data analyses. Abbreviations: TsA, Trichostatin A

	Experiment I - Acquisition and Low-Dose Tests		Experiment II - Extinction and Reinstatement
	Vehicle	TsA	Vehicle	TsA
Enriched (EC)	5	8	5	7
Isolated (IC)	7	8	4	6
Standard (SC)	6	8	5	7