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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Anal Bioanal Chem. 2019 Aug 1;411(24):6435–6447. doi: 10.1007/s00216-019-02024-5

Fig. 8.

Fig. 8

The trajectory on PCA plot for patient #11, #27, #36, and #47. #11 and #27 are the upgrade case (initially listed as potential ARDS on the first day) and #36 and #47 are recovery cases (extubated and discharged from ICU 24–48 hours after the last test). The bottom/top zone below/above the boundary line represents respectively the ARDS/non-ARDS region using the breath analysis method

Note: If the breath test results do not match the clinical adjudication, we consider the test as “misclassification” when calculating the overall classification accuracy, even for the cases like #36.3 and #47.4 that suggest that the breath analysis was able to predict the trajectory of ARDS (i.e., earlier diagnosis).