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. 2019 Sep 3;9:12684. doi: 10.1038/s41598-019-49205-x

Table 3.

Distribution of number of cups of coffee products and its association with breast cancer riska.

Cups of coffee drinking per day, n (%) Controls (N = 1 013) Cases (N = 1 156) Crude OR (95% CI)bc Adjusted OR (95% CI)bcd
Overall coffee
Non-habitual coffee drinker 834 (82.3) 918 (79.4) 1.00 1.00
<1 cup/day 51 (5.0) 77 (6.7) 1.37 (0.95–1.98) 1.22 (0.80–1.85)
≥1 cup/day 128 (12.6) 161 (13.9) 1.14 (0.89–1.47) 1.09 (0.81–1.46)
Instant coffee
Non-habitual coffee drinker 900 (88.8) 974 (84.3) 1.00 1.00
<1 cup/day 37 (3.7) 63 (5.4) 1.55 (1.02–2.35) 1.36 (0.85–2.17)
≥1 cup/day 76 (7.5) 119 (10.3) 1.42 (1.05–1.93) 1.45 (1.02–2.06)
Two/Three in one
   Non-habitual coffee drinker 998 (98.5) 1 119 (96.8) 1.00 1.00
   <1 cup/day 4 (0.4) 10 (0.9) 2.27 (0.71–7.27) 2.91 (0.61–13.91)
   ≥1 cup/day 11(1.1) 27 (2.3) 2.23 (1.10–4.52) 2.51 (1.14–5.57)
Brewed coffee
Non-habitual coffee drinker 954 (94.2) 1 112 (96.3) 1.00 1.00
<1 cup/day 24 (2.4) 25 (2.2) 0.95 (0.54–1.67) 0.67 (0.35–1.29)
≥1 cup/day 35 (3.5) 18 (1.6) 0.47 (0.26–0.83) 0.40 (0.20–0.76)
Homemade coffee
   Non-habitual coffee drinker 889 (97.7) 902 (97.5) 1.00 1.00
   <1 cup/day 10 (1.0) 13 (1.1) 1.18 (0.52–2.71) 0.93 (0.37–2.33)
   ≥1 cup/day 15 (1.5) 13 (1.1) 0.79 (0.37–1.66) 0.65 (0.27–1.60)
Restaurant coffee
   Non-habitual coffee drinker 977 (96.4) 1 139 (98.5) 1.00 1.00
   <1 cup/day 17 (1.7) 12 (1.0) 0.64 (0.30–1.35) 0.44 (0.19–1.03)
   ≥1 cup/day 19 (1.9) 5 (0.4) 0.24 (0.09–0.64) 0.23 (0.08–0.65)
Others e
Non-habitual coffee drinker 897 (98.2) 898 (97.4) 1.00 1.00
<1 cup/day 6 (0.6) 12 (1.0) 1.82 (0.68–4.86) 2.30 (0.69–7.64)
≥1 cup/day 13 (1.3) 14 (1.2) 0.98 (0.46–2.09) 0.80 (0.35–1.80)

aParticipants with missing values were excluded from the analysis.

bThe reference group was defined as the participants who did not have a habitual coffee consumption (i.e., coffee drinking vs. non-coffee drinking; instant coffee drinking vs. non- coffee drinking).

cParticipants who drank both instant coffee and brewed coffee were excluded in the logistic regression models.

dAdjusted for age at interview, educational attainment, family breast cancer history, previous history of benign breast diseases, body mass index (BMI), shift work experiences, smoking status, alcohol and tea drinking consumption, and deep fried food and green vegetable consumption. eOther coffee referred to those who drank decaffeinated coffee or had no preferable coffee products.