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. 2019 Sep 3;9:12684. doi: 10.1038/s41598-019-49205-x

Table 6.

Association between controls and breast cancers in coffee products consumption stratified by menopausal statusa.

Characteristics Pre-menopausal Post-menopausal
Control n = 341 All cases n = 388 Adjusted ORbcd (95% CI) Control n = 616 All cases n = 695 Adjusted ORbcd (95% CI)
Coffee drinking, n (%) 67 (19.6) 78 (20.1) 1.00 (0.65–1.54) 106 (17.2) 149 (21.4) 1.15 (0.83–1.60)
   Instant coffee 42 (12.3) 60 (15.5) 1.44 (0.86–2.44) 67 (10.9) 114 (16.4) 1.52 (1.03–2.25)
     Two/Three in one 3 (0.9) 13 (3.4) 5.37 (1.14–25.38) 12 (1.9) 23 (3.3) 1.82 (0.79–4.17)
   Brewed coffee 24 (7.0) 18 (4.6) 0.51 (0.21–1.19) 34 (5.5) 23 (3.3) 0.40 (0.20–0.83)
     Homemade coffee 9 (2.6) 6 (1.5) 0.61 (0.13–2.91) 15 (2.4) 19 (2.7) 0.75 (0.31–1.84)
     Restaurant coffee 15 (4.4) 11 (2.8) 0.48 (0.17–1.30) 21 (3.4) 4 (0.6) 0.13 (0.04–0.49)
   Otherse 8 (2.3) 8 (2.1) 0.72 (0.25–2.11) 10 (1.6) 18 (2.6) 1.41 (0.57–3.47)

aParticipants with missing values were excluded from the analysis.

bThe reference group was defined as the participants who did not have a habitual coffee consumption (i.e., coffee drinking vs. non-coffee drinking; instant coffee drinking vs. non- coffee drinking).

cParticipants who drank both instant coffee and brewed coffee were excluded in the logistic regression models. dAdjusted for age at interview, educational attainment, family breast cancer history, previous history of benign breast diseases, body mass index (BMI), shift work experiences, smoking status, alcohol and tea drinking consumption, and deep fried food and green vegetable consumption.

eOther coffee referred to those who drank decaffeinated coffee or had no preferable coffee products.