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. 2019 Sep 3;10:3719. doi: 10.1038/s41467-019-11724-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Chromosomal and positional distribution of runs of homozygosity (ROHs) detected in 125 EI cases (F_ROH > 0.1). Each row, with possibly multiple segments, represents a unique participant. Segments are groups by autosomal chromosomes from chromosome 1 (bottom of each panel) to chromosome 22 (top of each panel) ROHs are grouped in 6 length categories: between 1.5 and 5 Mb (a), between 5 and 10 Mb (b), between 10 and 20 Mb (c), between 20 and 50 Mb (d), between 50 and 100 Mb (e), and above 100 Mb (f). f also show inbreeding coefficients of individuals harbouring the largest ROHs