Table 1.
Parameter | Month | LVFW pacing Simulation | LVFW Pacing Experiment (Van Oosterhout et al., 1998) | LBBB Experiment (Vernooy et al., 2004) | LVFW Pacing Experiment (Prinzen et al., 1995) |
---|---|---|---|---|---|
LVEDV (% of Normal”) | 0 | 100 | 100 ± 27.8 | 100 ± 29.8 | 100 |
2 | 102.3 | — | 117.5 ± 12.8 | — | |
4 | 104.6 | — | 129.8 ± 50.9R | — | |
6 | 109 | 107.4 ± 29.9M | — | — | |
8 | 113.7 | — | — | — | |
LVEF (%) | 0 | 48.7 | 35.3 ± 7.0 | 43 ± 4 | 100 |
2 | 48.3 | — | — | — | |
4 | 48.6 | — | 33 ± 6R | — | |
6 | 47.8 | 39.6 ± 8.9M | — | — | |
8 | 48.3 | — | — | — | |
LVESV (% Change) | 0 | 100 | 100 | — | 100 |
2 | 104.9 | — | — | — | |
4 | 108.7 | — | — | — | |
6 | 118.5 | — | — | — | |
8 | 126.4 | — | — | — | |
Early activated region thickness (% change) | 0 | 100L | 100L | 100C | 100L |
2 | 90.3L | 90.7 ± 8.7L | — | 88.9 ± 6.8L,R | |
4 | 83.9L | 87.0 ± 7.2L | — | 79.7 ± 8.0L,R,* | |
6 | 81.3L | 86.5 ± 16.7L,R | — | — | |
8 | 79.6L | — | — | — | |
Late activated region thickness (% Change) | 0 | 100C | 100C | 100L | 100C |
2 | 105.2C | 108.4 ± 11.3C | — | 96.8C,M | |
4 | 113.7C | 110.5 ± 16.8C | — | 103.0 ± 7.5C,M,* | |
6 | 119.6C | 122.5 ± 11.3C,R | — | — | |
8 | 127.5C | — | — | — | |
RV thickness (% Change) | 0 | 100 | 100 | 100 | 100 |
2 | 91.4 | — | — | — | |
4 | 91.1 | — | — | — | |
6 | 88.6 | — | — | — | |
8 | 88.7 | — | — | — |
Mdenotes no significant change over time; Rdenotes significant change over time (p < 0.05).
LDenotes LVFW Thickness; Cdenotes septum thickness.
*Denotes 3 months; —denotes not reported or measured.