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. 2019 Aug 28;10:1112. doi: 10.3389/fphys.2019.01112

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Copyright © 2019 Fan, An, Wang, Chen, Liu, Liu, Ma and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Based on sequence-pairing prediction predicted 15 circRNAs targeted circRNA–miRNA–mRNA/gene network. The results of miRNA-binding sites predicted by mirSVR, and targeted TargetScan and miRanda predicted miRNAs and mRNAs, were considered. The red circles represent mRNAs and green nodes represent miRNAs.