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. 2019 Sep 3;9:12676. doi: 10.1038/s41598-019-49179-w

Table 3.

Risk factors predicting survival.

Mean overall survival, month (95% CI) p
Age 0.043
Age >65 years (n = 67) 59.5 (43.2–75.8)
Age <65 years (n = 52) 103.4 (77.3–129.4)
Diabetes 0.143
Yes (n = 35) 55.1 (32.6–77.6)
No (n = 84) 88.0 (68.8–107.3)
Jaundice 0.989
Yes (n = 33) 74.7 (48.9–100.5)
No (n = 86) 80.6 (61.7–99.4)
Weight loss 0.388
Yes (n = 52) 85.7 (62.3–109.1)
No (n = 65) 74.1 (53.4–94.8)
Pain 0.114
Yes (n = 42) 64.7 (41.5–87.9)
No (n = 77) 87.3 (67.0–107.7)
Pos. lymph node status* <0.001
Yes (n = 57) 43.2 (27.0–59.3)
No (n = 58) 110.7 (87.7–133.7)
Resection margin status <0.001
R0 (n = 108) 81.4 (64.8–97.9)
R1 (n = 8) 16.6 (5.3–27.9)
Perineural invasion 0.001
Yes (n = 30) 30.0 (17.4–42.5)
No (n = 83) 87.6 (68.7–106.4)
Lymphangiosis 0.016
Yes (n = 39) 60.7 (37.2–84.1)
No (n = 61) 94.6 (73.5–115.8)
Adjuvant CTx 0.243
Yes (n = 11) 32.7 (21.2–44.3)
No (n = 108) 81.9 (65.3–98.5)

Mean overall survival and the 95% (CI) were analyzed by the Kaplan-Meier method using the log-rank test.