Figure 7.

Comparison of the In Vivo and Ex Vivo Bioluminescence Signals in the Draining Lymph Nodes after Intradermal Injection of 5 μg sa-RNA-LNPs

The in vivo bioluminescence signals were measured 5 h after intradermal injection. Twenty-four hours after injection of the sa-RNA-LNPs, mice were euthanized, and the subiliac lymph nodes were excised and dripped with luciferin immediately before measurement. LN+, ipsilateral lymph node draining the injection spot. LN−, the contralateral lymph node. Horizontal bars represent the mean (n = 4). **p < 0.01; ***p < 0.001.