Table 3.
Activity of methylgerambullin against E. histolytica (A) and methylgerambullin and aglafoline against G. duodenalis (B).
| A - Entamoeba histolytica | G [μM] | σg |
|---|---|---|
| Methylgerambullin | ||
| 24 h | 14.5 | 1.36 |
| 48 h | 17.5 | 1.59 |
| Control metronidazole | ||
| 24 h | 2.40 | |
| 48 h |
1.40 |
|
| B - Giardia duodenalis |
G [μM] |
σg |
| Methylgerambullin | ||
| 24 h | 14.6 | 2.85 |
| 48 h | 36.6 | 6.08 |
| Aglafoline | ||
| 24 h | 17.2 | |
| 48 h | 7.71 | |
| Control metronidazole | ||
| 24 h | 3.15 | |
| 48 h | 1.93 | |
Test of methylgerambullin and metronidazole (control) against E. histolytica (A) as well as methylgerambullin, aglafoline and metronidazole (control) against G. duodenalis (B). The geometric means G [μM] of EC50 values are shown for three experiments (methylgerambullin) or two experiments (metronidazole, aglafoline), in addition the geometric standard deviations σg are given where three experiments were performed.