Table 3.

Correlational analyses of free-water, CSF, PET imaging, and clinical measures.

	MMSE		MoCA		AV45		CSF Aβ1–42		CSF p-tau		CSF t-tau
	ρ	FDR P-value	ρ	FDR P-value	ρ	FDR P-value	ρ	FDR P-value	ρ	FDR P-value	ρ	FDR P-value
Left Hippocampus Free-water	−0.45⁎	8.90E-06	−0.38⁎	0.005	0.30⁎	8.60E-03	−0.28⁎	0.004	0.09	0.47	0.21	0.06
RightHippocampus Free-water	−0.42⁎	8.60E-06	−0.42⁎	3.45E-04	0.27⁎	0.003	−0.27⁎	0.008	0.11	0.36	0.13	0.27

The correlation coefficients and the corresponding p value are listed for each association, *indicates significant correlations (FDR p < .05). Abbreviations: Aβ = amyloid beta, AV45 = florbetapir, CSF = cerebrospinal fluid, MMSE = Mini-Mental State Examination, MoCA = Montreal Cognitive Assessment, p-tau = phosphorylated tau, and t-tau = total tau.