Fig. 5. Inhibition of extracellular signal-regulated kinase (ERK) phosphorylation suppressed the invasive activity of CD81-knockdown bladder cancer cells. The ERK inhibitor, U0126, was administered to T24 and J82 cell lines. (A) Inhibition of ERK phosphorylation by U0126 in T24 and J82 bladder cancer cells. (B) Invasive activity of U0126-treated T24 and J82 bladder cancer cells (stained with crystal violet, ×400). DMSO, dimethylsulfoxide; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.
