Table 1.
Cases (n=90) | SHIP2 protein expression in BC tissue (n) | P-value | ||
---|---|---|---|---|
Low expression | High expression | |||
Age (years) | ||||
<45 | 41 | 21 | 20 | >0.05 |
≥45 | 49 | 21 | 28 | |
T stage | ||||
T1 | 23 | 10 | 13 | >0.05 |
T2 | 15 | 7 | 8 | |
T3-4 | 52 | 25 | 27 | |
N stage | ||||
N0 | 25 | 10 | 15 | >0.05 |
N1-2 | 65 | 32 | 33 | |
TNM stage | ||||
I | 24 | 13 | 15 | <0.0001 |
II | 34 | 8 | 22 | |
III–IV | 32 | 21 | 11 | |
Differentiation | ||||
Well/moderate | 44 | 29 | 15 | <0.0001 |
Poor | 46 | 13 | 33 |
Notes: Low/high expression was obtained by the sample median. Pearson χ2 test. P<0.05 was considered statically significant.
Abbreviations: BC, breast cancer; SHIP2, SH2-containing inositol 5′-phosphatase 2.