Table 4.
Prevalence of virulence traits in relation to ST131 status among 216 UTI E. coli isolates from women
| Virulence gene | No. (%) of strains | P-value | No. (%) of ST131 strains | P-value | ||
|---|---|---|---|---|---|---|
| ST131 (n=41) | non-ST131 (n=175) | O16-ST131 (n=14) | O25b-ST131 (n=27) | |||
| Adhesins | ||||||
| fimH | 41 (100) | 145 (82.9) | 0.004 | 14 (100) | 27 (100) | – |
| F10 papA | 39 (95.1) | 46 (26.3) | 0.000 | 13 (92.9) | 26 (96.3) | 1.000 |
| fimAvMT78 | 0 (0) | 9 (5.1) | 0.294 | 0 (0) | 0 (0) | – |
| papC | 7 (17.1) | 37 (21.1) | 0.560 | 2 (14.3) | 5 (18.5) | 1.000 |
| papEF | 8 (19.5) | 42 (24.0) | 0.540 | 2 (14.3) | 6 (22.2) | 0.847 |
| sfa/focDE | 0 (0) | 5 (2.9) | 0.586 | 0 (0) | 0 (0) | – |
| afa/draBC | 11 (26.8) | 15 (8.6) | 0.003 | 5 (35.7) | 6 (22.2) | 0.580 |
| afa FM955459 | 7 (17.1) | 5 (2.9) | 0.001 | 3 (21.4) | 4 (14.8) | 0.923 |
| bmaE | 4 (9.8) | 3 (1.7) | 0.033 | 2 (14.3) | 2 (7.4) | 0.882 |
| gafD | 0 (0) | 1 (0.6) | 1.000 | 0 (0) | 0 (0) | – |
| iha | 31 (75.6) | 64 (36.6) | 0.000 | 9 (64.3) | 22 (81.5) | 0.405 |
| Toxins | ||||||
| cdtB | 0 (0) | 0 (0) | – | 0 (0) | 0 (0) | – |
| sat | 22 (53.7) | 55 (31.4) | 0.007 | 2 (14.3) | 20 (74.1) | 0.000 |
| cnf1 | 11 (26.8) | 19 (10.9) | 0.008 | 4 (28.6) | 7 (25.9) | 1.000 |
| hlyA | 7 (17.1) | 5 (2.9) | 0.001 | 2 (14.3) | 5 (18.5) | 1.000 |
| Siderophores | ||||||
| iucD | 39 (95.1) | 106 (60.6) | 0.000 | 13 (92.9) | 26 (96.3) | 1.000 |
| iroN | 2 (4.9) | 47 (26.9) | 0.002 | 1 (7.1) | 1 (3.7) | 1.000 |
| iutA | 39 (95.1) | 105 (60.0) | 0.000 | 12 (85.7) | 27 (100) | 0.111 |
| fyuA | 32 (78.0) | 105 (60.0) | 0.031 | 10 (71.4) | 22 (81.5) | 0.734 |
| Capsules | ||||||
| kpsM II | 36 (87.8) | 118 (67.4) | 0.009 | 11 (78.6) | 25 (92.6) | 0.425 |
| kpsM II-K2 | 2 (4.9) | 58 (33.1) | 0.000 | 1 (7.1) | 1 (3.7) | 1.000 |
| kpsM II-K5 | 19 (46.3) | 56 (32.0) | 0.083 | 4 (28.6) | 15 (55.6) | 0.100 |
| kpsM III | 0 (0) | 3 (1.7) | 1.000 | 0 (0) | 0 (0) | – |
| Miscellaneous | ||||||
| cvaC | 0 (0) | 19 (10.9) | 0.057 | 0 (0) | 0 (0) | – |
| iss | 2 (4.9) | 35 (20.0) | 0.021 | 0 (0) | 2 (7.4) | 0.539 |
| traT | 36 (87.8) | 105 (60.0) | 0.001 | 14 (100) | 22 (81.5) | 0.224 |
| ibeA | 0 (0) | 11 (6.3) | 0.210 | 0 (0) | 0 (0) | – |
| malX | 39 (95.1) | 63 (36.0) | 0.000 | 13 (92.9) | 26 (96.3) | 1.000 |
| usp | 40 (97.6) | 52 (29.7) | 0.000 | 13 (92.9) | 27 (100) | 0.341 |
| tsh | 0 (0) | 14 (8.0) | 0.128 | 0 (0) | 0 (0) | – |
| ompT | 37 (90.2) | 92 (52.6) | 0.000 | 13 (92.9) | 24 (88.9) | 1.000 |
| Virulence score | 12.5 (7–17)a | 8.2 (1–20)a | 0.000 | 11.6 (7–17)a | 12.9 (11–16)a | 0.072 |
Note: aThe value denotes the mean and range.