Fig.1.

The growth rate of A375 cell line was inhibited by ß-elemene. A375 cells were cultivated in 96-well plates at a density of 5×103 cells/well and treated with different concentrations of ß-elemene in different time periods: A. 24, B. 48, and C. 72 hours. Cell proliferation was evaluated using the MTT assay. The IC₅₀ value is a concentration of a drug that inhibits cell proliferation by 50% in comparison to the control. The data are shown as the means ± SD of three independent experiments. Asterisks indicate significant differences. ****; P<0.0001, ***; P<0.001, **; P<0.01, *; P<0.05, NS; Non significant, IC₅₀: The half maximal inhibitory concentration, and CI; Confidence interval.