Table 2.
Blood pressure, urinary, and serum biochemical variables in adults with mildly to moderately elevated blood pressure (n 96) during the reduced-salt and usual-salt dietary periods.
| Dietary Period | Usual-Salt | Reduced-Salt | p-Value 1 | ||
|---|---|---|---|---|---|
| Blood pressure: | |||||
| Systolic (mmHg) | 134.3 | 12.1 | 131.0 | 11.0 | <0.0001 |
| Diastolic (mmHg) | 84.7 | 8.5 | 84.6 | 8.2 | 0.815 |
| Urine 2: | |||||
| Sodium (mmol/day) | 106.0 | 53.6 | 77.6 | 35.6 | <0.0001 |
| Potassium (mmol/day) | 97.6 | 51.5 | 95.9 | 51.5 | 0.771 |
| Calcium (mmol/day) | 4.36 | 2.35 | 4.10 | 2.52 | 0.183 |
| NTx (nmol BCE/mmol creatinine) | 55.0 | 36.7 | 54.6 | 42.9 | 0.654 |
| Serum 3: | |||||
| 25(OH)D (nmol/L) | 53.6 | 16.7 | 52.6 | 14.7 | 0.414 |
| BAP (U/L) | 27.2 | 9.3 | 27.7 | 9.5 | 0.137 |
| Osteocalcin (g/L) | 12.5 | 4.3 | 13.0 | 5.6 | 0.208 |
| CTx (g/L) | 0.69 | 0.31 | 0.69 | 0.29 | 0.964 |
| PTH (pg/mL) | 64.2 | 31.0 | 62.1 | 30.9 | 0.271 |
1P-value for treatment effect; there was no significant carry-over effects (p > 0.13, in all cases). 2 Based on n = 84 due to exclusion of subjects who missed a urine collection at week 5 or 10 (n = 8) or had suspected inaccurate urine collections at week 5 or week 10 (n = 4). 3 Based on n = 90. NTx, N-telopeptides of Type I collagen; BCE, bone collagen equivalents; 25(OH)D, 25-hydroxyvitamin D; BAP, Bone-specific alkaline phosphatase; CTx, C-telopeptides of Type I collagen; PTH, parathyroid hormone.