Table 2.
Odds ratios (ORs) for hyperuricemia and corresponding 95% CI by quartile of DII scores in KoGES_CAVAS cohort.
| Quartile of DII | ||||||
|---|---|---|---|---|---|---|
| First (Lowest) | Second | Third | Fourth (Highest) | p for Trend a | Continuous DII | |
| TOTAL | ||||||
| Range | −7.3344~−1.2409 | −1.2408~−0.2501 | −0.2499~1.5499 | 1.5513~7.0740 | ||
| Cases/controls | 349/3047 | 367/3047 | 391/3047 | 408/3045 | ||
| Odds ratio (95% CI) | ||||||
| Crude | 1.00 | 1.05 (0.90−1.23) b | 1.12 (0.96–1.31) | 1.17 (1.01–1.36) | 0.03 | 1.03 (1.00–1.05) |
| Multivariate adjusted | 1.00 | 1.05 (0.89–1.25) | 1.01 (0.92–1.30) | 1.23 (1.03–1.46) | 0.02 | 1.04 (1.01–1.07) |
| MEN c | ||||||
| Range | −7.3344~−1.3572 | −1.3565~−0.3522 | −0.3520~1.4001 | 1.4012~6.9009 | ||
| Cases/controls | 212/1057 | 217/1057 | 220/1057 | 226/1056 | ||
| Odds ratio (95% CI) | ||||||
| Crude | 1.00 | 1.02 (0.83–1.26) | 1.04 (0.84–1.28) | 1.07 (0.87–1.31) | 0.53 | 1.02 (0.98–1.05) |
| Multivariate adjusted | 1.00 | 1.03 (0.82–1.29) | 1.00 (0.80–1.26) | 1.10 (0.87–1.39) | 0.49 | 1.02 (0.98–1.06) |
| WOMEN | ||||||
| Range | −7.3009~−1.1924 | −1.1915~−0.1928 | −0.1922~1.6153 | 1.6154~7.0740 | ||
| Cases/controls | 126/1990 | 148/1989 | 170/1991 | 196/1989 | ||
| Odds ratio (95% CI) | ||||||
| Crude | 1.00 | 1.18 (0.92–1.50) | 1.35 (1.06–1.71) | 1.56 (1.23–1.96) | <0.0001 | 1.07 (1.03–1.11) |
| Multivariate adjusted | 1.00 | 1.11 (0.85–1.45) | 1.17 (0.90–1.52) | 1.35 (1.03–1.77) | 0.02 | 1.04 (0.99–1.01) |
Q1 indicates participants having the lowest DII values, the least pro-inflammatory level; Q4 the highest, the most pro-inflammatory level. DII, Dietary inflammatory index. a Tests for trends were performed for continuous variable using categorical DII scores by quartiles. b Data are presented as odds ratios (ORs) with correspondent 95% confidence intervals (CI) and are adjusted for gender (for total subjects), smoking status, drinking status, education, body-mass index (BMI), age, caloric per day, history of diabetes, history of hypertension, and region. c p value for interaction was calculated as the cross-product of gender (men and women) and the continuous DII score in the model was 0.20.