Table 4.
Multivariable adjusted ORs of hyperuricemia and corresponding 95% CI by quartile of flavonoids of DII components in women in KoGES_CAVAS cohort.
| Quartile of Components | |||||
|---|---|---|---|---|---|
| DII components (Flavonoids) | First (lowest) | Second | Third | Fourth (highest) | P for trend a |
| Flavan-3-ol (mg) | |||||
| Cases/controls | 190/1990 | 167/1990 | 147/1990 | 136/1989 | |
| Multivariate adjusted | 1.00 | 0.89 (0.71–1.12) b | 0.85 (0.68–1.08) | 0.78 (0.61–0.99) | 0.04 |
| Flavones (mg) | |||||
| Cases/controls | 183/1990 | 163/1989 | 167/1990 | 127/1990 | |
| Multivariate adjusted | 1.00 | 0.95 (0.76–1.20) | 0.97 (0.77–1.22) | 0.75 (0.59–0.96) | 0.04 |
| Flavonols (mg) | |||||
| Cases/controls | 181/1989 | 164/1990 | 166/1990 | 129/1990 | |
| Multivariate adjusted | 1.00 | 0.94 (0.75–1.18) | 0.98 (0.78–1.23) | 0.76 (0.59–0.97) | 0.06 |
| Flavonones (mg) | |||||
| Cases/controls | 196/1989 | 150/1991 | 161/1989 | 133/1990 | |
| Multivariate adjusted | 1.00 | 0.83 (0.66–1.05) | 0.89 (0.71–1.11) | 0.75 (0.59–0.95) | 0.04 |
| Flavonoids (mg) | |||||
| Cases/controls | 187/1990 | 165/1989 | 156/1991 | 132/1989 | |
| Multivariate adjusted | 1.00 | 0.92 (0.74–1.16) | 0.90 (0.71–1.13) | 0.75 (0.59–0.96) | 0.03 |
Q1 indicates participants having the lowest DII values, the least pro-inflammatory level; Q4 the highest, the most pro-inflammatory level. DII, Dietary inflammatory index; Flavonoids = flavan-3-ol+flavones+flayonols+flayonones. a Tests for trends were performed for continuous variables using categorical component scores by quartiles. b Data are presented as odds ratios (ORs) with correspondent 95% confidence intervals (CI) and are adjusted for smoking status, drinking status, education, body-mass index (BMI), age, history of diabetes, history of hypertension, and region.