Table 3.

Known genes associated with uterine corpus endometrial carcinoma development, metastasis, and prognosis in the core module network.

Gene Symbol	Full Name	Gene Function	References
AURKA	aurora kinase A	The protein encoded by this gene is a cell cycle-regulated kinase. It has a significant relationship with the prognosis of UCEC and can be used as a clinical biomarker for UCEC.	[73,74]
CHTF18	chromosome transmission fidelity factor 18	The protein encoded by the gene is a component of a replication factor C (RFC) complex. The mutation of this gene is associated with the pathogenesis of UCEC.	[75]
EZH2	enhancer of zeste 2 polycomb repressive complex 2 subunit	This gene encodes a member of the Polycomb-group (PcG) family and is related to the prognosis of UCEC. It can be used as a prognostic marker for UCEC.	[76,77]
FBXW7	F-box and WD repeat domain containing 7	This gene encodes a member of the F-box protein family. It is associated with the development and prognosis of UCEC.	[78,79]
JAG1	jagged canonical Notch ligand 1	This gene encodes a jagged 1 protein. It is closely related to the invasion and prognosis of UCEC.	[80]