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. 2019 Aug 2;55(8):431. doi: 10.3390/medicina55080431

Table 1.

NETosis markers in human kidney disease.

Kidney Disease NETosis Markers References
Acute Kidney Injury

  • NE

  • Citrullinated histone H3

 [11]

  • Circulating DNA

  • Nucleosomes

 [39]
Lupus Nephritis

  • Cell free DNA

  • NET protecting antibodies

 [41,42]

  • NE

  • MPO

  • Histone H2A

 [45]
Small vessels and ANCA-associated vasculitis

  • Nucleosomes

  • MPO

 [61,68]

  • MPO

  • Histone H2A

  • Histone H2B

  • PAD4

  • Citrullinated histone H3

 [66]

  • MPO

  • Citrullinated histone H3

 [69]

Abbreviations: NE, neutrophil elastase; MPO, myeloperoxidase; PAD4, peptidylarginasedeiminase 4; ANCA, anti-neutrophil cytoplasm antibodies.