Table 5.

Comparative study of insulin release kinetics from uncoated and coated SiNP at gastric and intestinal conditions.

Gastric Conditions
	Free Insulin	Ins-SiNP	Ins-SiNP-CH	Ins-SiNP-SA
Zero order
r2	0.9738	0.9929	0.9835	0.9754
AIC	39.86	31.45	35.63	38.98
First order
r2	0.9982	0.9944	0.9992	0.9978
AIC	18.29	29.58	11.58	19.63
Second-order
r2	0.9985	0.9994	0.9993	0.9982
AIC	19.02	13.01	12.46	20.10
Boltzmann
r2	*	0.9999	0.9999	*
AIC	*	14.94	15.04	*
Hyperbolic
r2	0.9962	09943	0.9982	0.9961
AIC	81.51	102.75	54.89	81.33
Peppas
r2	0.9943	0.9952	0.9965	0.9942
AIC	15.71	15.37	15.08	15.62
Intestinal Conditions
	Free Insulin	Ins-SiNP	Ins-SiNP-CH	Ins-SiNP-SA
Zero order
r2	0.9427	0.9761	0.9507	0.9481
AIC	61.09	54.21	59.00	58.24
First order
r2	0.9986	0.9973	0.9991	0.9993
AIC	29.70	35.06	23.91	21.65
Second-order
r2	0.9801	0.9983	0.9861	0.9839
AIC	52.21	29.60	48.35	48.51
Boltzmann
r2	0.9992	0.9993	0.9993	*
AIC	28.41	25.75	25.16	*
Hyperbolic
r2	0.9937	0.9947	0.9957	0.9965
AIC	39.04	39.17	34.67	31.40
Peppas
r2	0.9443	0.9877	0.9794	0.9791
AIC	53.04	47.52	50.28	49.12

* Kinetic fitting model interrupted.