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. 2019 Aug 8;11(8):1835. doi: 10.3390/nu11081835

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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C/EBPα (mRNA and protein) and mir-137-3p expression profile during adipogenesis in chronic/intermittent normoglycemic (N) and hyperglycemic (H) conditions. (a) The relative levels of mRNA expression and (b) protein concentration of C/EBPα and (c) relative levels of miR-137-3p expression evaluated after completion of proliferation, differentiation and maturation of visceral cells. Data are expressed as mean ± SEM. Differences in expression levels between two particular culture variants were evaluated using a two-tailed t-test. One-way ANOVA with a post hoc Tukey test was used for calculation of statistical significance of changes observed during ADG in NG (NN vs N, NNN vs N, NNN vs NN) and HG (HH vs H, HHH vs H, HHH vs HH). *** p ≤ 0.001; ** p ≤ 0.01; * p ≤ 0.05.