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. 2019 Aug 19;9(8):381. doi: 10.3390/biom9080381

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The relationship between TH+ cell density and motor behaviour in the cylinder, rotarod, and adjusted stepping tests following 20 µg LPS injection and PBM treatment. (a) A significant positive relationship between TH+ cell density and cylinder test performance was found for the LPS group at post-surgery day 5 (* p < 0.05) but not for the PBM group. Vehicle: n = 7; LPS: n = 9; PBM: n = 8. (b) A significant positive relationship existed between TH+ cell density and rotarod performance for LPS rats at post-surgery day 4 (* p < 0.05), but not the PBM group. Vehicle: n = 7; LPS: n = 9; PBM: n = 9. (c) No significant relationship existed between the contralateral (right) paw forehand stepping performance and TH+ cell density for LPS or PBM rats at post-surgery day 4. Vehicle: n = 7; LPS: n = 9; PBM: n = 9. (d) A significant positive relationship existed between TH+ cell density and contralateral paw backhand stepping performance for LPS rats at post-surgery day 4 (* p < 0.05), but not PBM-treated rats. Vehicle: n = 7; LPS: n = 9; PBM: n = 9. r values represent Pearson’s correlation coefficient.