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. 2019 Jul 19;9(9):3009–3022. doi: 10.1534/g3.119.400470

Figure 2.

Figure 2

Increase in premorbid, OC-like marble burying in Cyfip1N/- and Cyfip1J/- mice. (A): Schematic of the marble burying apparatus. (B,C): Cyfip1N/- mice buried more marbles with greater than 50% coverage than wild-type Cyfip1N/N mice [B: U(102) = 1050; *P = 0.031; two-tailed], and had a greater average percent marble burial across the six marbles [C: effect of Genotype: F(1,96) = 7.1; *P = 0.009; no effect of PO and no Genotype x PO interaction; p’s > 0.05]. (D,E): Similarly, Cyfip1J/- mice buried more marbles with greater than 50% coverage than Cyfip1J/J mice [D: U(137) = 1884; *P = 0.019, two-tailed], and also had a greater average percent marble burial across the six marbles [E: Effect of Genotype: F(1,134) = 4.2; *P = 0.042; no effect of PO and no Genotype x PO interaction; p’s > 0.05]. Data are presented as the mean ± SEM.