Skip to main content
. 2019 Sep;189(9):1814–1830. doi: 10.1016/j.ajpath.2019.05.022

Figure 4.

Figure 4

Retinal iron accumulation in the LS-HepcKO mice occurs despite an intact blood-retinal barrier (BRB). A and B: Albumin immunolabeling to test for BRB integrity in cryosections from the control (A) and LS-HepcKO (B) mice at 6 months. C: Western analysis showing albumin protein levels in the neurosensory retina (NSR) in the LS-HepcKO mice versus controls at 3 months and relative pixel density of Western analysis albumin bands corrected for glyceraldehyde-3-phosphate dehydrogenase (GAPDH). n = 4 per genotype (A and B). Scale bars = 100 μm (A and B). GCL, ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; ONL, outer nuclear layer; OPL, outer plexiform layer; RPE, retinal pigment epithelium.