Table 1.

Hematic parameters.

		Group
	Week	Normal Diet + Vehicle	HFD + Vehicle	HFD + P. vulgaris	HFD + Metformin	HFD + Atorvastatin
Glucose (mg/dL)	13	101.0 ± 3.4	139.3 ± 6.9 *	103.0 ± 5.1^	132.0 ± 9.9	133.0 ± 6.2
	15	99.0 ± 10.1	149.5 ± 3.9 **	103.0 ± 8.0^^	113.3 ± 7.4 ^	112.8 ± 7.1 ^
	17	103.3 ± 6.4	138.5 ± 9.1 *	127.8 ± 2.0 ^^	121.0 ± 5.9 ^	146.3 ± 5.5
	19	99.3 ± 4.6	137.3 ± 9.4 **	112.0 ± 4.4 ^	116.3 ± 5.7 ^	137.3 ± 14.0
Triglycerides (mg/dL)	13	62.0 ± 6.9	132.3 ± 11.3 *	123.0 ± 18.0	105.0 ± 14.6	102.0 ± 9.0 ^
	15	72.3 ± 13.6	135.3 ± 6.0 **	86.5 ± 10.7 ^	93.3 ± 10.4 ^	103.3 ± 9.4 ^
	17	78.4 ± 2.7	136.8 ± 2.3 **	105.3 ± 7.8 ^^	113.8 ± 5.8 ^	108.8 ± 7.2 ^^
	19	75.8 ± 11.0	133.5 ± 7.7 **	107.5 ± 9.3 ^^	118.3 ± 3.7	104.0 ± 3.0 ^^
Total cholesterol (mg/dL)	13	<100	133.7 ± 4.4 **	104.3 ± 3.5 ^^	128.6 ± 8.2	105.0 ± 6.0 ^^
	15	105.0 ± 5.0	135.8 ± 1.3 **	103.0 ± 2.3 ^^	118.3 ± 7.2	105.0 ± 4.3 ^^
	17	107.0 ± 1.2	147.0 ± 2.8 **	123.0 ± 6.4 ^^	139.3 ± 12.5	109.5 ± 5.0 ^^
	19	103.8 ± 4.1	147.3 ± 4.1 **	100.5 ± 7.6 ^^	103.9 ± 9.2 ^^	76.4 ± 1.4 ^^
HDL (mg/dL)	19	51.8 ± 8.5	62.3 ± 7.0	41.7 ± 10.2	59.1 ± 10.5	46.8 ± 9.5
LDL (mg/dL)	19	43.8 ± 6.7	62.3 ± 7.0	38.4 ± 6.3 ^^	46.0 ± 9.4 ^	50.2 ± 3.0 ^^

Effects of HFD and treatments on glucose, triglycerides, and total cholesterol blood concentration at weeks 13, 15, 17, and 19. At week 19, HDL and LDL values were also assessed. Animals were fed with normal or HFD diets from week 1. P. vulgaris extract (500 mg/kg), metformin (100 mg/kg), and atorvastatin (10 mg/kg) were administered daily per os, starting from week 11. Each value represents the mean ± S.E.M. of at least 12 mice per group. * p < 0.05 and ** p < 0.01 vs. normal diet + vehicle; ^ p < 0.05 and ^^ p < 0.01 vs. HFD + vehicle.