Table 1.
Demographic and clinical characteristics of 90 patients with ulcerative colitis.
| Variables | N = 90 |
|---|---|
| Median age, years (IQR) | 45 (32–56) |
| Males, n (%) | 41 (46%) |
| White race, n (%) | 86 (96%) |
| Non-Hispanic ethnicity, n (%) | 90 (100%) |
| Mean body mass index, kg/m2 (SD) | 27.9 (6.8) |
| Smoking status, n (%) | |
| Never-smoker | 60 (67%) |
| Ex-smoker | 28 (31%) |
| Current smoker | 2 (2%) |
| Other comorbid diseases, n (%) | |
| Diabetes mellitus | 4 (4%) |
| Hypertension | 5 (6%) |
| None | 81 (90%) |
| Median UC duration, years (IQR) | 9.9 (4.2–17.2) |
| UC location, n (%) | |
| Proctitis/proctosigmoiditis | 10 (11%) |
| Left-sided colitis | 25 (28%) |
| Extensive colitis | 55 (61%) |
| UC current medication, n (%) | |
| 5-Aminosalicylates | 38 (42%) |
| Immunomodulators | 25 (28%) |
| Systemic corticosteroids | 16 (18%) |
| Biologic agents | 40 (44%) |
| None | 10 (11%) |
| ClinPRO2 | |
| Rectal bleeding, n (%) | |
| Score 0: no blood seen | 46 (51%) |
| Score 1: streaks of blood less than half the time | 20 (22%) |
| Score 2: obvious blood most of the time | 17 (19%) |
| Score 3: blood passes alone | 7 (8%) |
| Stool frequency, n (%) | |
| Score 0: normal | 27 (30%) |
| Score 1: 1–2 per day more than normal | 17 (19%) |
| Score 2: 3–4 per day more than normal | 14 (16%) |
| Score 3: ≥5 per day more than normal | 32 (35%) |
| Mayo endoscopic subscore, n (%) | |
| Score 0: normal | 10 (11%) |
| Score 1: erythema, decreased vascular pattern | 26 (29%) |
| Score 2: marked erythema, absent vascular pattern, friability, erosion | 18 (20%) |
| Score 3: spontaneous bleedings, ulceration | 36 (40%) |
| Median SIBDQ (IQR) | 48.5 (34–59) |
| Median EQ5D3L-TTO (IQR) | 0.827 (0.778–1) |
| Median WPAI (IQR) | |
| % overall work impairment | 36 (0–80) |
| Median FACIT-F (IQR) | 33.1 (13.1) |
| Median HADS-Depression (IQR) | 4 (1–7) |
| Median HADS-Anxiety (IQR) | 5 (3–9) |
UC, ulcerative colitis; IQR, interquartile range; SD, standard deviation; ClinPRO2, the self- rated rectal bleeding and stool frequency using 6-points of the partial Mayo score; SIBDQ, Short Inflammatory Bowel Disease Questionnaire; EQ5D3L-TTO, European Quality of Life 5-Dimensions 3-Level, time-trade-off; WPAI, Work Productivity and Activity Impairment questionnaire; FACIT-F, Functional Assessment of Chronic Illness Therapy-Fatigue; HADS, Hospital Anxiety and Depression Scale.