Figure 1.
The resveratrol rice DJ526 increased the lifespan of Drosophila melanogaster. (A) ORR males, (B) ORR females, (C) Harwich males and (D) Harwich females. Ctrl represents standard cornmeal medium; RS represents cornmeal medium supplemented with resveratrol at 31.54 µg/L, the equivalent amount of resveratrol found in the DJ526 media; DJ represents the medium in which 50% of cornmeal was replaced with Dongjin rice; DJRS represents the medium in which 50% of cornmeal was replaced with Dongjin rice and supplemented with resveratrol at 31.54 µg/L; and DJ526 represents the medium in which 50% of the cornmeal was replaced with the resveratrol rice DJ526 (Table S1). For the lifespan assay, the survival rate of 150 flies from each group was monitored with medium change every 4 days. Comparisons were made using log-rank tests. The p values (log-rank tests) for each strain and each sex were as follows. (A) ORR male flies: DJ526 versus Ctrl (p < 0.0001), RS (p < 0.0001), DJ (p = 0.0228), and DJRS (p = 0.1074), respectively. (B) ORR female flies: DJ526 versus Ctrl (p < 0.0001), RS (p < 0.0001), DJ (p = 0.0259), and DJRS (p = 0.4557), respectively. (C) Harwich male flies: DJ526 versus Ctrl (p < 0.0001), RS (p < 0.0001), DJ (p = 0.0721), and DJRS (p = 0.0788), respectively. (D) Harwich female flies: DJ526 versus Ctrl (p = 0.0001), RS (p < 0.0001), DJ (p = 0.0219), and DJRS (p = 0.0794), respectively. The percentage of surviving flies is shown along with the maximum lifespan in each group (n = 150).