Figure 1.

Domain structure of Cyprinus carpio Mef2 (myocyte enhancer factor 2) proteins. The N-terminal region of each Mef2 protein harbors the evolutionarily conserved MADS-box and MEF2 domains. The third homologous structure located in the highly variable C-terminal region, namely the HJURP_C domain, is not identified in Mef2b, Mef2ca1, and Mef2cb by Conserved Domain Search. The numbers indicated are amino acid positions of one isoform. D-Mef2 represents the Mef2 protein of Drosophila melanogaster. The ohnologs with the same structural feature are labeled together as "1,2". The question mark denotes that the protein sequence of Mef2d2 is incomplete at present.