. 2019 Aug 17;55(8):496. doi: 10.3390/medicina55080496

Table 1.

Immunoreactivity of cytokines, chemokines, remodelling factors, regulatory factors, and antimicrobial peptides in the control group by semi-quantitative grading. Summary of median values and interquartile ranges.

KERRYPNX	Control (N = 49)
	Bronchial Epithelium	Bronchial Mucosal Connective Tissue	Bronchial Mucosal Blood Vessel Wall	Bronchial Smooth Muscle	Bronchial Glands	Bronchial Cartilage	Bronchial Epithelium	Bronchial Mucosal Connective Tissue
	Mdn (Q₂) IQR
IL-1α	0/+	0/+	0	0	0	+	0/+	+
IL-1α	1.0	1.0	0.5	0	0	0.5	1.0	1.0
IL-4	+/++	0/+	0/+	0	0/+	0/+	+	+/++
IL-4	1.5	0.5	1.0	1.0	1.0	1.0	1.25	1.5
IL-6	+	0/+	0/+	0	0	+	+	+/++
IL-6	1.5	0.5	1.0	0.5	0.5	1.5	0.5	0.5
IL-7	+/++	0/+	+	0	0/+	++	+	+/++
IL-7	1.0	1.0	0.75	1.0	1.0	1.0	1.25	1.5
IL-8	0/+	+	++	0/+	+	++/+++	+	++
IL-8	0.5	1.0	2.0	0.5	1.0	0.5	1.0	1.5
IL-10	+/++	+	+	0/+	0/+	++	+	+/++
IL-10	1.0	0.5	1.0	0.5	1.0	1.0	1.5	1.0
IL-12	+/++	0/+	+	+/++	+/++	+	+	0/+
IL-12	1.0	0.5	0.5	1.0	0.5	1.0	0.5	0.5
TNF-α	0	0/+	0	0	0	0/+	0/+	+/++
TNF-α	0.5	1.0	0.5	0.5	0.5	0.5	0.5	1.5
MMP-2	+	0/+	0/+	0	0/+	+/++	+	+/++
MMP-2	1.0	0.5	1.5	1.0	0.5	1.5	1.0	1.0
TIMP-2	+	0/+	+	0/+	0/+	++	+/++	+/++
TIMP-2	1.0	0.5	1.0	0.5	0	1.0	1.0	1.0
TGF-β1	+	0/+	0/+	0	0/+	+	+	+
TGF-β1	1.0	0.25	1.0	0.5	1.0	0.5	1.0	1.25
Hsp-70	+	0/+	0/+	0	0/+	+/++	+/++	+
Hsp-70	0.5	0.5	1.0	0.5	0.5	0.5	0.5	1.0
hBD-2	0/+	0/+	+	0	0/+	++	+/++	+/++
hBD-2	1.0	1.0	2.0	0.5	0.5	1.5	0.5	1.5
hBD-3	0/+	0/+	0/+	0/+	0/+	+/++	+/++	+
hBD-3	0.5	0.5	1.5	1.0	1.0	1.0	1.0	2.0
hBD-4	0/+	0/+	0/+	0	0	+	+/++	+
hBD-4	0.75	1.0	1.5	0.5	1.0	1.5	0.5	2.5

Semi-quantitative grading scores are displayed with rank values. “Control”– Control group, “N”–Number of the study subjects, “Mdn”– Median value, “IQR”– interquartile range (with 95% CI–95% Confidence interval), “Q₂”–2nd Quartile (50th percentile value).