Figure 1.

Puumala virus (PUUV) Phylogenetic tree constructed from the complete coding sequence of the small (S) segment by maximum likelihood (ML) method implemented in PhyML 3.0 under the general time reversible (GTR) +G+I substitution model. Branches of the tree clustered within a same PUUV lineage are collapsed to make overall tree visually clear. Eight known PUUV lineages are indicated. The list of sequences belonging to each lineage is indicated in Table S1 together with their geographic origin. Nodes representing most recent common ancestor of North-Scandinavian (N-SCA) lineage, Finnish (FIN), Russian (RUS) and Latvian (LAT) lineages, and Alpe-Adrian (ALAD) and Central European (CE) lineages are indicated, respectively, by the letters A, B, and C.